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Dr Paul Brennan
Dr Paul Brennan
BMedSci(Hons), MBBS, FRCP
Clinical Genetics
37 reviews
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About

Dr Brennan's interest in genetics started as a medical student in the 1980s when the medical speciality of clinical genetics was in its infancy. After a research degree studying genes in the developing heart, he completed his medical training and undertook postgraduate training in adult medicine and paediatrics before specialist training in Clinical Genetics.

Dr Brennan was appointed as an NHS Consultant in Clinical Genetics in 2002 with the Northern Genetics Service based in Newcastle upon Tyne. After opening a new satellite clinical genetics department in Middlesbrough, he was appointed to the role of Clinical Director of the Northern Genetics Service in 2008, managing a clinical and laboratory team providing genetics diagnostics for the population of North East England and North Cumbria.

Dr Brennan has been Clinical Lead for Cardiac and Endocrine Genetics for the Northern Genetics Service since 2003; he was Clinical Lead for Cancer Genetics for County Durham, Tees Valley and North Yorkshire from 2002 to 2018 and is now Clinical Lead for the whole North East region.

A particular interest is the use of new technology and novel clinical pathways to improve diagnosis and management for people living with rare inherited disease. Between 2014 and 2018 he was Clinical Programme Director for the North East & North Cumbria NHS Genomic Medicine Centre, overseeing the introduction of whole genome sequencing into routine care as part of the 100,000 Genomes Project. He is engaged in a number of collaborative research projects, all of which are focused on improving diagnosis and treatment.

Dr Brennan is a keen and popular teacher and lectures to a wide range of undergraduate and postgraduate audiences in the UK and overseas. He teaches genetics for a week each year at Newcastle University's Medical School in Malaysia.

 

www.genomics.expert

 

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Special Interests

Dr Brennan has a long experience of diagnosing and managing hereditary diseases in adults and young people. In general his specialist areas are:


A. Inherited cardiovascular disorders, for example:

  • Brugada syndrome
  • Long QT syndrome
  • Familial hypertrophic and dilated cardiomyopathy
  • Arrhythmogenic right ventricular cardiomyopathy
  • Sudden unexplained death
  • Familial thoracic aortic aneurysm
  • Marfan syndrome, Loeys Dietz syndrome and Meester-Loeys syndrome
  • Vascular Ehlers Danlos syndrome

B. Inherited connective tissue disorders, including

  • classical Ehlers Danlos syndrome
  • hypermobile Ehlers Danlos syndrome

C. Inherited cancer syndromes, for example:

  • Hereditary breast/ovarian cancer
  • Cowden's disease
  • Lynch syndrome
  • Familial Adenomatous Polyposis
  • Hereditary leiomyomatosis / renal cell carcinoma syndrome
  • Birt Hogg Dube syndrome
  • Li Fraumeni syndrome

C. Inherited endocrine syndromes, for example:

  • Familial paragangliomatosis
  • Von Hippel Lindau disease
  • Multiple endocrine neoplasis types 1 & 2 and familial medullary thyroid cancer)

Education

  • Bachelor of Medical Science (Human Genetics) Newcastle University
  • Bachelor of Medicine and Bachelor of Surgery, Newcastle University

Professional Qualifications:

  • MRCP (Edinburgh)
  • FRCP (London)

Verified Patient Reviews

All reviews are from verified patients who have seen this specialists. If you'd like more information on reviews, please have a look at our help center.

Review Breakdown

5 Stars
37
4 Stars
0
3 Stars
0
2 Stars
0
1 Star
0

Overall

5.0

Explanation

5.0

Bedside Manner

5.0

Overall
Explanation
Bedside Manner
Great and informative appointment. Dr Brennan was extremely helpful, answered all my questions and provided great assurance throughout the appointment and testing process.
Patient seen for:Clinical Genetics
Verified Patient
24-02-2020
Helpful?0
Overall
Explanation
Bedside Manner
My wife and I booked an appointment with Dr Brennan who made himself available at a convenient time for us. He was very clear in his explanation of our particular issue and has been very helpful in his follow up with the next steps. I would certainly recommend Dr Brennan
Patient seen for:Clinical Genetics
Verified Patient
29-01-2020
Helpful?0
Overall
Explanation
Bedside Manner
Although I had a short interaction with Dr. Brennan I found his explanation very clear. He was very interested in my family history and my concern relating to breast cancer risk. He presented to me with a graphical support the various genes which may impact the development of risk cancer and recommended, based on his experience, the best test that I should take. I felt very comfortable in his presence and trust his experience and knowledge in the matter.
Patient seen for:Clinical Genetics
Verified Patient
24-01-2020
Helpful?0
Overall
Explanation
Bedside Manner
Extremely professional and ensured the patient was at ease through out the consultation. Prompt with intimating results, and very comprehensive in his consultation. I would strongly recommend Dr Brennan.
Patient seen for:Clinical Genetics
Verified Patient
09-12-2019
Helpful?0
Overall
Explanation
Bedside Manner
Doctor Brennan has been very helpful throughout the entire diagnose period. His follow up and explanation have been crystal clear and meant a lot to us while we going through that time. Thank you again for your expertise and kind thought!
Verified Patient
09-12-2019
Helpful?0
Overall
Explanation
Bedside Manner
We had a consultation with Dr Brennan regarding a hereditary genetic condition affecting our family. He provided a very clear explanation of the issues and was clearly very knowledgeable in the field. He had a very reassuring and patient manner. He offered plenty of time and opportunity for questions. He was extremely quick and responsive to all our enquiries and gave some practical advice and appropriate guidance about the issues of testing. We felt very confident in all aspects of his care and would have no doubt in highly recommending him to others.
Patient seen for:Genetic Consultation
Verified Patient
25-11-2019
Helpful?0
Overall
Explanation
Bedside Manner
I was seen for a very rare disease Looking forward to have the diagnosis
Verified Patient
25-10-2019
Helpful?0
Overall
Explanation
Bedside Manner
Dr Brennan was so reassuring thoughout the whole of our chat. He made me feel a lot less stressed and ensured I was ok with what he was saying. I loved that he asked my opinion and how I felt instead of just giving me information. He gave me a perspective on the situation that within a stressful time I wasn’t able to imagine. Amazing help and professionalism
Patient seen for:Genetic Consultation
Verified Patient
11-10-2019
Helpful?0
Overall
Explanation
Bedside Manner
Dr Brennan was very polite and welcoming and made our baby feel at ease. He has a very warm manner which I personally think is vital when dealing with children and he is softly spoken also; so he is not in any way intimidating to young children. He took the time to listen to our concerns and didn’t make us feel we were imagining there was a medical issue which was how we were made to feel when speaking to an NHS doctor. He was efficient and I note in his follow up report he had taken on board everything we had mentioned. Very happy with the service.
Patient seen for:Genetic Procedures
Verified Patient
11-10-2019
Helpful?0
Overall
Explanation
Bedside Manner
I took myself and my two children along to see Dr Brennan at the international gene clinic in Newcastle. I myself, had been misdiagnosed for many years and have suffered many complications along the way. I noticed my children were beginning to suffer similar symptoms as myself. I had a scan which found a hindbrain hernia which could be connected to a connective tissue disorder, that's when I set off on my journey to find someone who could give me the correct diagnosis along with my children. I chose Dr Brennan as he highly recommended, he has a lovely way in which he listens to your problems, he is very thorough and explains in detail why you could be experiencing certain symptoms and how certain systems in the body are affected. It was a pleasure for me and my family to see Dr Brennan and I would highly recommend him as he diagnosed each of us and has guided us in the right direction of Drs who will be able to help manage our condition.Many Thanks
Patient seen for:hEDS
Verified Patient
10-10-2019
Helpful?0