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Mr Aquilina is a Consultant Paediatric Neurosurgeon at Great Ormond Street Hospital. He has a sub-specialty interest in the management of spasticity, and he was responsible for establishing the selective dorsal rhizotomy service for cerebral palsy at Great Ormond Street Hospital.

He earned his medical degree in 1995 from the University of Malta. In 2009, he completed neurosurgery training in Bristol and received an MD (Doctor of Medicine) from the University of Bristol for his work on intraventricular haemorrhage and hydrocephalus in preterm babies. He went on to complete a one-year clinical fellowship in paediatric neurosurgery at St Jude Children's Research Hospital in Memphis, Tennessee, where he focused on paediatric neuro-oncology. In 2010, he became a Consultant Neurosurgeon in Bristol and joined Great Ormond Street Hospital in 2012.